Annual report pursuant to Section 13 and 15(d)

Summary of Stock Option Activity (Details)

v3.22.1
Summary of Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based Payment Arrangement [Abstract]    
Options outstanding at beginning 465,393 377
Weighted average exercisable price $ 5.53 $ 7,446.69
Weighted average remaining contractual terms (years), outstanding at beginning 9 years 3 months 18 days 5 years 3 months 18 days
Intrinsic value, outstanding at beginning of period $ 511,518
Options, granted 368,500 465,017
Weighted average exercise price, granted $ 1.93 $ 0.47
Weighted average remaining contractual terms (years), granted 10 years 10 years
Options, exercised
Weighted average exercise price, exercised
Options, forfeited
Weighted average exercise price, forfeited
Options, expired (1) (1)
Weighted average exercise price, expired $ 139,158.00
Options, outstanding at end 833,892 465,393
Weighted average exercise price, outstanding at end of period $ 3.91 $ 5.53
Weighted average remaining contractual terms (years), outstanding at ending 8 years 8 months 12 days 9 years 3 months 18 days
Intrinsic value, outstanding at end of period $ 87,553 $ 511,518
Vested and expected to vest at end 268,185 376
Weighted average exercise price, vested and expected to vest at end $ 10.04 $ 6,977.42
Weighted average remaining contractual terms (years), vested and expected to vest 8 years 3 months 18 days 4 years 3 months 18 days
Intrinsic value, vested and expected to vest end of period $ 46,449
Vested and expected to vest at end 830,292 465,393
Weighted average exercise price, vested and expected to vest at end $ 3.91 $ 5.53
Weighted average remaining contractual terms (years), vested and expected to vest 8 years 8 months 12 days 9 years 3 months 18 days
Intrinsic value, vested and expected to vest end of period $ 86,703 $ 511,518