Annual report pursuant to Section 13 and 15(d)

Stock-Based Compensation - Summary of Stock Option Activity (Details)

v3.8.0.1
Stock-Based Compensation - Summary of Stock Option Activity (Details) - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]    
Options, Outstanding at beginning of period 11,446 9,364
Options, Granted 3,280
Options, Exercised
Options, Forfeited
Options, Expired (144) (1,198)
Options, Outstanding at end of period 11,302 11,446
Options, Exercisable at end of period 9,835 8,996
Options, Vested and expected to vest at end of period 11,302 11,446
Weighted Average Exercise Price, Outstanding at beginning of period $ 367.08 $ 498.60
Weighted Average Exercise Price, Granted 16.44
Weighted Average Exercise Price, Exercised
Weighted Average Exercise Price, Forfeited
Weighted Average Exercise Price, Expired 8,719.64 495.96
Weighted Average Exercise Price, Outstanding at end of period 264.26 367.08
Weighted Average Exercise Price, Exercisable at end of period 287.31 507.72
Weighted Average Exercise Price, Vested and expected to vest at end of period $ 264.26 $ 367.08
Weighted Average Remaining Contractual Terms (Years), Outstanding 8 years 2 months 12 days  
Weighted Average Remaining Contractual Terms (Years), Outstanding 7 years 3 months 19 days 8 years 2 months 12 days
Weighted Average Remaining Contractual Terms (Years), Exercisable 8 years 3 months 19 days 7 years 10 months 25 days
Weighted Average Remaining Contractual Terms (years), Vested and expected to vest 7 years 3 months 19 days 8 years 8 months 12 days
Intrinsic Value, Outstanding at beginning of period
Intrinsic Value, Outstanding at end of period
Intrinsic Value, Exercisable at end of period
Intrinsic Value, Vested and expected to vest at end of period